Divergent local and systemic antitumor response in primary uveal melanomas.
Lucibello F, Lalanne AI, Le Gac AL, Soumare A, Aflaki S, Cyrta J, Dubreuil L, Mestdagh M, Salou M, Houy A, Ekwegbara C, Jamet C, Gardrat S, Le Ven A, Bernardeau K, Cassoux N, Matet A, Malaise D, Pierron G, Piperno-Neumann S, Stern MH, Rodrigues M, Lantz O. J Exp Med,  2024.

A conserved transcriptional program for MAIT cells across mammalian evolution.
Hélène Bugaut, Yara El Morr , Martin Mestdagh, Aurélie Darbois, Rafael A Paiva, Marion Salou, Laetitia Perrin, Mariela Fürstenheim, Anastasia du Halgouet, Linda Bilonda-Mutala, Anne-Laure Le Gac, Manon Arnaud, Ahmed El Marjou, Coralie Guerin, Atitheb Chaiyasitdhi, Julie Piquet, David M Smadja, Agata Cieslak, Bernhard Ryffel, Valdone Maciulyte, James M A Turner, Karine Bernardeau, Xavier Montagutelli, Olivier Lantz, François Legoux. J Exp Med,  2024.

Persistent CD8 T Cell Marks Caused by the HCMV Infection in Seropositive Adults: Prevalence of HLA-E-Reactive CD8 T Cells.
Amélie Rousselière and Béatrice Charreau. Cells,  2023.

Excess of Guide RNA Reduces Knockin Efficiency And Drastically Increases On-Target Large Deletions.
Vanessa Chenouard, Isabelle Leray, Laurent Tesson, Severine Remy, Alasdair Allan, Daniel Archer, Adam Caulder, Agnès Fortun, Karine Bernardeau, Yacine Cherifi, Lydia Teboul, Laurent David, Ignacio Anegon.
IScience,  2023.

Distinctive phenotype for HLA-E- versus HLA-A2-restricted memory CD8 αβT cells in the course of HCMV infection discloses features shared with NKG2C+CD57+NK and δ2-γδT cell subsets.
Rousselière A, Gérard N, Delbos L, Guérif P, Giral M, Bressollette-Bodin C, Charreau B.
Front Immunol,  2022.

Mapping and Characterization of HCMV-Specific Unconventional HLA-E-Restricted CD8 T Cell Populations and Associated NK and T Cell Responses Using HLA/Peptide Tetramers and Spectral Flow Cytometry.
Amélie Rousselière, Laurence Delbos, Céline Bressollette, Maïlys Berthaume, Béatrice Charreau.
Int. J. Mol. Sci. 2022.

Highly Efficient Knockin in Human iPS Cells and Rat Embryos by CRISPR/Cas9 Molecular Optimization.
Vanessa Chenouard, Isabelle Leray, Laurent Tesson, Séverine Remy, Agnès Fortun, Karine Bernardeau, Yacine Cherifi, Laurent David, Ignacio Anegon.
BioRxiv,  2021.

A novel and efficient approach to high-throughput production of HLA-E/peptide monomer for T-cell epitope screening.
Juliette Vaurs,  Gaël Douchin, Klara Echasserieau, Romain Oger, Nicolas Jouand, Agnès Fortun, Leslie Hesnard, Mikaël Croyal, Frédéric Pecorari, Nadine Gervois, Karine Bernardeau.
Scientific Reports,  2021, volume 11, Article number: 17234 (2021)

Phase I/II clinical trial of adoptive cell transfer of sorted specific T cells for metastatic melanoma patients.
Brigitte Dréno, Amir Khammari, Agnès Fortun, Virginie Vignard, Soraya Saiagh, Tiffany Beauvais, Nicolas Jouand, Sylvain Bercegay, Sylvain Simon, François Lang & Nathalie Labarrière.
Cancer Immunology, Immunotherapy (2021). doi: 10.1007/s00262-021-02961-0.

VLDL (Very-Low-Density Lipoprotein)-Apo E (Apolipoprotein E) May Influence Lp(a) (Lipoprotein [a]) Synthesis or Assembly.
Croyal M, Blanchard V, Ouguerram K, Chétiveaux M, Cabioch L, Moyon T, Billon-Crossouard S, Aguesse A, Bernardeau K, Le May C, Flet L, Lambert G, Hadjadj S, Cariou B, Krempf M, Nobécourt-Dupuy E.
Arterioscler Thromb Vasc Biol. 2020 Mar;40(3):819-829. doi: 10.1161/ATVBAHA.119.313877

SPECT-CT Imaging of Dog Spontaneous Diffuse Large B-Cell Lymphoma Targeting CD22 for the Implementation of a Relevant Preclinical Model for Human.
Etienne F, Berthaud M, Nguyen F, Bernardeau K, Maurel C, Bodet-Milin C, Diab M, Abadie J, Gouilleux-Gruart V, Vidal A, Bourgeois M, Chouin N, Ibisch C, Davodeau F.
Front Oncol. 2020 Feb 7;10:20. doi: 10.3389/fonc.2020.00020. eCollection 2020.

Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8+ T Cells in Human Donors Allows the Detection of a TEMRA Subpopulation.
Céline Vandamme,  Rebecca Xicluna,  Leslie Hesnard,  Marie Devaux,  Nicolas Jaulin,  Mickaël Guilbaud,  Johanne Le Duff,  Célia Couzinié,  Philippe Moullier,  Xavier Saulquin and  Oumeya Adjali.
Front. Immunol., 21 January 2020. doi.org/10.3389/fimmu.2019.03110

Host-range shift between emerging P[8]-4 rotavirus and common P[8] and P[4] strains.
Amira Khachou, Béatrice Le Moullac-Vaidye, Cécile Peltier, Adrien Breiman, Berthe-Marie Imbert-Marcille, Nathalie Ruvoen-Clouet, Mahjoub Aouni, Maha Mastouri, Slaheddine Chouchane, Jacques Le Pendu.
The Journal of Infectious Diseases, 2020. doi.org/10.1093/infdis/jiaa122

Molecular mechanisms of lineage decisions in metabolite-specific T cells.
François Legoux, Jules Gilet, Emanuele Procopio, Klara Echasserieau, Karine Bernardeau and Olivier Lantz.
Nature Immunology 2019. https://doi.org/10.1038/s41590-019-0465-3.

Ex vivo evolution of human antibodies by CRISPR-X: from a naive B cell repertoire to affinity matured antibodies.
Marie-Claire Devilder, Melinda Moyon, Laetitia Gautreau-Rolland, Benjamin Navet, Jeanne Perroteau, Florent Delbos, Marie-Claude Gesnel, Richard Breathnach, and Xavier Saulquin.
BMC Biotechnol. 2019 Feb 18;19(1):14. doi: 10.1186/s12896-019-0504-z.

Tetramer-Based Enrichment of Preexisting Anti-AAV8 CD8+ T Cells in Human Donors Allows the Detection of a TEMRA Subpopulation.
Céline Vandamme,  Rebecca Xicluna,  Leslie Hesnard,  Marie Devaux,  Nicolas Jaulin,  Mickaël Guilbaud,  Johanne Le Duff,  Célia Couzinié,  Philippe Moullier,  Xavier Saulquin and  Oumeya Adjali.
Front. Immunol., 21 January 2020,  doi.org/10.3389/fimmu.2019.03110

Chapitre de livre « Principes des techniques de biologie moléculaire et génomique » : Fiche « Production de protéines recombinantes”.
Tagu D, Jaubert-Possamai S, Méreau A., coord, Echasserieau K, Douchin G, Bernardeau K, Pecorari F. Edition Quae, 2018

Histo-blood group antigen-binding specificities of human rotaviruses are associated with gastroenteritis but not with in vitro infection.
Laure Barbé, Béatrice Le Moullac-Vaidye, Klara Echasserieau, Karine Bernardeau, Thomas Carton, Nicolai Bovin, Johan Nordgren, Lennart Svensson, Nathalie Ruvoën-Clouet and Jacques Le Pendu
Sci Rep. 2018 Aug 28;8(1):12961. doi: 10.1038/s41598-018-31005-4.

HCMV triggers frequent and persistent UL40-specific unconventional HLA-E-restricted CD8 T-cell responses with potential autologous and allogeneic peptide recognition.
Jouand N, Bressollette-Bodin C, Gérard N, Giral M, Guérif P, Rodallec A, Oger R, Parrot T, Allard M, Cesbron-Gautier A, Gervois N*, Charreau B*.
PLoS Pathog. 2018 Apr 30;14(4):e1007041. doi: 10.1371/journal.ppat.1007041. eCollection 2018 Apr.

Generation of Discriminative Human Monoclonal Antibodies from Rare Antigen-specific B Cells Circulating in Blood.
Devilder MC, Moyon M, Saulquin X, Gautreau-Rolland L
J Vis Exp. 2018 Feb 6;(132). doi: 10.3791/56508.

TCR Analyses of Two Vast and Shared Melanoma Antigen-Specific T Cell Repertoires: Common and Specific Features
Simon S, Wu Z, Cruard J, Vignard V, Fortun A, Khammari A, Dreno B, Lang F, Rulli S, Labarriere N
Front Immunol. 2018 Aug 30;9:1962. doi: 10.3389/fimmu.2018.01962. eCollection 2018.

Emergence of High-Avidity Melan-A-Specific Clonotypes as a Reflection of Anti-PD-1 Clinical Efficacy.
Simon S, Vignard V, Varey E, Parrot T, Knol AC, Khammari A, Gervois N, Lang F, Dreno B, Labarriere N.
Cancer Res. 2017 Dec 15;77(24):7083-7093. doi: 10.1158/0008-5472.CAN-17-1856. Epub 2017 Dec 6.

Neuroblastoma chemotherapy can be augmented by immunotargeting O-acetyl-GD2 tumor-associated ganglioside
Faraj S, Bahri M, Fougeray S, El Roz A, Fleurence J, Leclair MD, Thébaud E, Paris F, and Birklé S
Oncoimmunology. 2017 Sep 21;7(1):e1373232. doi: 10.1080/2162402X.2017.1373232. eCollection 2017.

Antigen-specific single B cell sorting and expression-cloning from immunoglobulin humanized rats: a rapid and versatile method for the generation of high affinity and discriminative human monoclonal antibodies
Ouisse LH, Gautreau-Rolland L, Devilder MC, Osborn M, Moyon M, Visentin J, Halary F, Bruggemann M, Buelow R, Anegon I, Saulquin X
BMC Biotechnol. 2017 Jan 9;17(1):3. doi: 10.1186/s12896-016-0322-5.

New synthesis of phenyl-isothiocyanate C-functionalised cyclams. Bioconjugation and (64)Cu phenotypic PET imaging studies of multiple myeloma with the te2a derivative
Halime Z, Frindel M, Camus N, Orain PY, Lacombe M, Bernardeau K, Chérel M, Gestin JF, Faivre-Chauvet A, Tripier R
Org Biomol Chem. 2016 Apr 12;14(15):3838. doi: 10.1039/c6ob90046a

Carcinoma-associated fucosylated antigens are markers of the epithelial state and can contribute to cell adhesion through CLEC17A (Prolectin)
Breiman A, López Robles MD, de Carné Trécesson S, Echasserieau K, Bernardeau K, Drickamer K, Imberty A, Barillé-Nion S, Altare F, Le Pendu J
Oncotarget. 2016 Mar 22;7(12):14064-82. doi: 10.18632/oncotarget.7476

PD-1 expression conditions T cell avidity within an antigen-specific repertoire
Sylvain Simon, Virginie Vignard, Laetitia Florenceau, B. Dreno, A. Khammari, F. Lang, and N. Labarriere.
Oncoimmunology. 2016; 5(1): e1104448.

Role of the MHC restriction during maturation of antigen-specific human T cells in the thymus
Hesnard L, Legoux F, Gautreau L, Moyon M, Baron O, Devilder MC, Bonneville M, Saulquin X
Eur J Immunol. 2016 Mar;46(3):560-9. doi: 10.1002/eji.201545951.

IL-9 promotes the survival and function of human melanoma-infiltrating CD4(+) CD8(+) double-positive T cells
Parrot T, Allard M, Oger R, Benlalam H, Raingeard de la Blétière D, Coutolleau A, Preisser L, Desfrançois J, Khammari A, Dréno B, Labarrière N, Delneste Y, Guardiola P, Gervois N.
Eur J Immunol. 2016 Jul;46(7):1770-82. doi: 10.1002/eji.201546061.

Targeting and killing glioblastoma with monoclonal antibody to O-acetyl GD2 ganglioside
Fleurence J, Cochonneau D, Fougeray S, Oliver L Geraldo F, Terme M, Dorvillius M, Loussouarn D, Vallette F, Paris F, Birklé S
Oncotarget. 2016 May 9. doi: 10.18632/oncotarget.9226

CD40L confers helper functions to human intra-melanoma class-I-restricted CD4+CD8+ double positive T cells
Parrot T, Oger R, Benlalam H, Raingeard de la Blétière D, Jouand N, Coutolleau A, Preisser L, Khammari A, Dréno B, Guardiola P, Delneste Y, Labarrière N, Gervois N.
Oncoimmunology. 2016 Oct 28;5(12):e1250991. doi: 10.1080/2162402X.2016.1250991. eCollection 2016.